Description
BASIC BACTERIOLOGY 1
1. Bacteria Compared with
Other Microorganisms 1
2. Structure of Bacterial Cells 4
3. Growth 15
4. Genetics 18
5. Classification of Medically Important
Bacteria 24
6. Normal Flora 26
7. Pathogenesis 31
8. Host Defenses 52
9. Laboratory Diagnosis 61
10. Antimicrobial Drugs:
Mechanism of Action 69
11. Antimicrobial Drugs: Resistance 87
12. Bacterial Vaccines 96
13. Sterilization & Disinfection 100
P A R T II
CLINICAL BACTERIOLOGY 105
14. Overview of the Major Pathogens & Introduction
to Anaerobic Bacteria 105
15. Gram-Positive Cocci 109
16. Gram-Negative Cocci 128
17. Gram-Positive Rods 135
18. Gram-Negative Rods Related to the
Enteric Tract 148
19. Gram-Negative Rods Related to the
Respiratory Tract 171
20. Gram-Negative Rods
Related to Animal Sources
(Zoonotic Organisms) 177
21. Mycobacteria 183
22. Actinomycetes 194
23. Mycoplasmas 197
24. Spirochetes 199
25. Chlamydiae 208
26. Rickettsiae 212
27. Minor Bacterial Pathogens 217
P A R T III
BASIC VIROLOGY 225
28. Structure 226
29. Replication 232
30. Genetics & Gene Therapy 244
31. Classification of Medically Important
Viruses 248
32. Pathogenesis 253
33. Host Defenses 260
34. Laboratory Diagnosis 266
35. Antiviral Drugs 269
36. Viral Vaccines 280
P A R T IV
CLINICAL VIROLOGY 285
37. DNA Enveloped Viruses 288
38. DNA Nonenveloped Viruses 304
39. RNA Enveloped Viruses 311
40. RNA Nonenveloped Viruses 333
41. Hepatitis Viruses 342
42. Arboviruses 354
43. Tumor Viruses 361
44. Slow Viruses & Prions 372
45. Human Immunodeficiency Virus 378
46. Minor Viral Pathogens 391
MYCOLOGY 397
47. Basic Mycology 397
48. Cutaneous & Subcutaneous Mycoses 403
49. Systemic Mycoses 407
50. Opportunistic Mycoses 414
P A R T VI
PARASITOLOGY 423
51. Intestinal & Urogenital—Protozoa 424
52. Blood & Tissue Protozoa 433
53. Minor Protozoan Pathogens 450
54. Cestodes 453
55. Trematodes 462
56. Nematodes 469
P A R T VII
IMMUNOLOGY 489
57. Immunity 489
58. Cellular Basis of the Immune Response 500
59. Antibodies 522
60. Humoral Immunity 531
61. Cell-Mediated Immunity 534
62. Major Histocompatibility Complex &
Transplantation 536
63. Complement 542
64. Antigen–Antibody Reactions in the
Laboratory 546
65. Hypersensitivity (Allergy) 557
66. Tolerance & Autoimmune Disease 567
67. Tumor Immunity 576
68. Immunodeficiency 578
P A R T VIII
ECTOPARASITES 585
69. Ectoparasites That Cause Human Disease 585
P A R T IX
INFECTIOUS DISEASES 593
70. Bone and Joint Infections 593
71. Cardiac Infections 598
Contributed by Brian S. Schwartz, MD
72. Central Nervous System
Infections 605
73. Gastrointestinal Tract Infections 614
Contributed by Peter Chin-Hong, MD
74. Pelvic Infections 622
Contributed by Peter Chin-Hong, MD
75. Upper Respiratory Tract Infections 629
Contributed by Peter Chin-Hong, MD
76. Lower Respiratory Tract Infections 635
Contributed by Peter Chin-Hong, MD
77. Skin and Soft Tissue Infections 641
Contributed by Brian S. Schwartz, MD
78. Urinary Tract Infections 649
Contributed by Brian S. Schwartz, MD
P A R T X
BRIEF SUMMARIES OF
MEDICALLY IMPORTANT
ORGANISMS 653
P A R T XI
CLINICAL CASES 691
P A R T XII
PEARLS FOR THE USMLE 701
P A R T XIII
USMLE (NATIONAL BOARD)
PRACTICE QUESTIONS 709
P A R T XIV
USMLE (NATIONAL BOARD)
PRACTICE EXAMINATION 751




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